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Metronidazole has demonstrated proof of carcinogenic action in numerous reports involving Long-term oral administration in mice and rats. Popular among the results within the mouse was the advertising of pulmonary tumorigenesis. This continues to be noticed in all six documented scientific studies in that species, like just one examine where the animals had been dosed on an intermittent routine (administration throughout every fourth 7 days only). At really higher dose levels (close to 500 mg/kg/working day), there was a statistically important boost in the incidence of malignant liver tumors in males.
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